Table 1.
Overview about the sensitivity and specificity of SpyGlass
First author, publication, year | Study design | Patient (n) | Sensitivity for visual diagnosisual diagnosis/biopsy | Specificity for visual diagnosis/biopsy | PPV for visual diagnosis/biopsy | NPV for visual diagnosis/biopsy | Accuracy for biopsy/visual diagnosis |
Chen[15], 2007 | Prospective study | 35 | 100%/71% | 77%/100% | 70%/100% | 100%/87% | |
Ramchandani et al, 2012 | Prospective study | 36 | 95%/82% | 79%/82% | 88%/100% | 92%/100% | 89%/82% |
Hartmann et al, 2012 | Retrospective analysis | 89 | /57% | /100% | /100% | /68% | /78% |
Chen et al, 2011 | Prospective study | 297 | 77.8%/48.9% | 82%/98% | 80%/100% | 80%/72% | 80%/75% |
Kalaitzakis et al, 2012 | Retrospective analysis | 141 | 72% | 97% | 93% | 86% | 88% |
PPV: Positive predictive value; NPV: Negative predictive value.