Table 4.

Defined functions for phosphorylation sites in PhosphoGRID 2.0

Effect on Function	Residuesa	Proteinsb
Specific effects on protein structure/function
Promotes a protein interaction	222	42
Inhibits a protein interaction	212	35
Modifies interaction with small molecule/ligand	11	7
Functional consequence of phosphorylation
Activates protein function	240	88
Inhibits protein function	124	27
Targets protein for degradation	92	24
Enhances protein stability	30	6
Modifies subcellular localization	126	51
Total	940	225
Increase from version 1.0	249	25

^aNumber of individual phosphorylated residues in PhospoGRID assigned the indicated function.

^bNumber of proteins in PhosphoGRID bearing a phosphoresidue assigned the indicated function.