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. Author manuscript; available in PMC: 2013 May 14.
Published in final edited form as: J Am Coll Cardiol. 2013 Jan 23;61(9):957–970. doi: 10.1016/j.jacc.2012.10.051

Figure 2. Association Between 9p21 and Multivessel CAD as Compared With Single-Vessel CAD.

Figure 2

Figure 2

Figure 2

(A) Odds ratio (OR)/copy of risk allele (allelic model).

(B) heterozygote risk versus homozygote non-risk (genotypic model), random-effects analysis;

(C) homozygote risk versus homozygotes non-risk (genotypic model), random-effects analysis. Total n = 20,987; 14,232 multivessel disease, 6,755 single-vessel disease. Non-European ancestry cohorts were not included in the Bayesian analysis. Bayesian analysis showed no distinguishable differences between rs10757278/rs1333049 and rs2383206, for which the marginal effect estimate was nearly identical. CI = confidence interval; Bayesian = Bayesian model; CDCS = Coronary Disease Cohort Study; Cleveland GB = Cleveland GeneBank Study; D+L = DerSimonian and Laird random effects model; EmCB = Emory Cardiovascular Biobank; IHCS = Utah Intermountain Heart Collaborative Study; OHGS = Ottawa Heart Genomics Study; SAS = Southampton Atherosclerosis Study.