Table 3.
Ability of WLE and AFV in detecting the highest histologic grade lesion in 56 patients with at least one OPL or cancer
| Highest histologic grade lesion in the patient | WLE
|
AFV
|
|||||
|---|---|---|---|---|---|---|---|
| None of the highest-grade lesions diagnosed | Some of the highest-grade lesions diagnosed* | All of the highest-grade lesions diagnosed | None of the highest-grade lesions diagnosed | Some of the highest-grade lesions diagnosed* | All of the highest-grade lesions diagnosed | P† | |
| Low-grade lesions | |||||||
| Parakeratosis with atypia (n = 8) | 5 | 2 | 1 | 1 | 2 | 5 | |
| Mild dysplasia (n = 21) | 11 | 6 | 4 | 2 | 5 | 14 | |
| Total | 16 | 8 | 5 | 3 | 7 | 19 | 0.001 |
| High-grade lesions | |||||||
| Moderate dysplasia (n = 8) | 2 | — | 6 | — | — | 8 | |
| Severe dysplasia (n = 2) | — | — | 2 | — | — | 2 | |
| CIS or micro invasive SCC (n = 7) | 1 | 2 | 4 | — | — | 7 | |
| Total | 3 | 2 | 12 | 0 | 0 | 17 | 0.22 |
| Cancers | |||||||
| Invasive SCC (n = 8) | 1 | 1 | 6 | — | 1 | 7 | |
| Other carcinoma (n = 2)‡ | 1 | — | 1 | — | — | 2 | |
| Total | 2 | 1 | 7 | 0 | 1 | 9 | 0.47 |
| Total | 21 | 11 | 24 | 3 | 8 | 45 | <0.001 |
*
Some, but not all, of the highest-grade lesions diagnosed.
†
P value for WLE findings compared with AFV calculated by two-tailed Fisher’s exact test.
‡
Includes one patient with adenocarcinoma (salivary gland carcinoma) and one with verrucous carcinomas with SCC component.