Table 3.
Conditional Analysis of Factors Associated with Inappropriate Antimicrobial Recommendations
Variable | Unadjusted odds ratio (95% CI*) | P value | Adjusted odds ratio† (95% CI*) | P value |
---|---|---|---|---|
Inaccurate communication (vs. accurate) | 1.8 (0.93–3.6) | 0.08 | 2.1 (1.0–4.4) | 0.05 |
| ||||
Patient age, years | 0.99 (0.97–1.0) | 0.17 | 0.98 (0.96–1.0) | 0.11 |
| ||||
Intensive care unit patient location (vs. ward) | 0.67 (0.30–1.5) | 0.34 | ||
| ||||
Surgical service caller (vs. non- surgical) | 1.4 (0.67–2.7) | 0.40 | ||
| ||||
Hospital length of stay, days | 0.99 (0.96–1.0) | 0.68 | ||
| ||||
Weekend day of call (vs. weekday) | 0.49 (0.24–1.0) | 0.05 | 0.56 (0.23–1.4) | 0.20 |
| ||||
Female patient sex (vs. male) | 1.0 (0.52–1.9) | 1.0 | ||
| ||||
Patient location prior to admission | ||||
Home | 1 | - | 1 | - |
Different acute care center | 1.2 (0.56–2.6) | 0.63 | 1.4 (0.59–3.3) | 0.46 |
Intermediate or long-term center | 7.2 (1.5–35.7) | 0.02 | 7.1 (1.3–37.7) | 0.02 |
| ||||
Caller length of training post graduate year 1 (vs. ≥2) | 0.81 (0.38–1.7) | 0.58 | ||
| ||||
Indication | ||||
Empiric | 1 | - | ||
Definitive | 1.1 (0.51–2.5) | 0.79 | ||
Prophylactic | 0.77 (0.13–4.6) | 0.78 | ||
| ||||
Charlson comorbidity index | 1.2 (1.0–1.4) | 0.02 | 1.2 (1.1–1.5) | 0.01 |
| ||||
Consult attending antimicrobial recommendation (vs. none) | 1.9 (0.35–9.9) | 0.46 | ||
| ||||
ASP‡ practitioner in hospital during call (vs. out of hospital) | 0.74 (0.37–1.5) | 0.39 | ||
| ||||
Call time after 5 p.m. (vs. before) | 2.2 (0.77–6.1) | 0.14 | 1.7 (0.49–5.8) | 0.41 |
Note: only inaccurate communications and potential confounders were included in the multivariable model.
95% confidence interval;
adjusted for other variables in the multivariable model;
antimicrobial stewardship program