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. Author manuscript; available in PMC: 2013 May 14.
Published in final edited form as: Future Virol. 2012 Jun 1;7(6):563–573. doi: 10.2217/fvl.12.45

Figure 1. Genetic mechanisms of viral diversity and genomic sequencing strategies.

Figure 1

(A) Example of recombination between ssRNA virus genomes (i.e., dengue) and reassortment between segmented RNA virus genomes (i.e., influenza A) coinfecting the same cell. (B) Schema of how consensus sequencing provides a homogeneous representation of a virus population while deep sequencing generates sequence reads that capture genetic diversity, but that may not be unambiguously assembled into individual genomic segments.