Table 1.
Drug Resistance Profiles and Subtypes Observed in Longitudinal Samples by Population-Based Sequencing
| Sample type | Time postdiagnosis (weeks)a | RT drug resistance mutations |
|---|---|---|
| Blood plasma | 1 | D67N, K70R, K101E, Y181C, G190A, T215L, K219E |
| 6 | D67N, K70R, K101E, Y181C, G190A, T215L, K219E | |
| 18 | D67N, K70R, K101E, Y181C, G190A, T215L, K219E | |
| 34 | D67N, K101E, Y181C, G190A, T215L, K219E | |
| 54 | Mix at multiple codons | |
| 85 | None | |
| 87 | None | |
| 89 | None | |
| 94 | Y181Y/C | |
| 98 | None | |
| Seminal plasma | 87 | None |
a
Antiretroviral treatment was started after the samples at 87 weeks postdiagnosis were taken. Population-based sequencing results of HIV-1 pol from blood plasma RNA and from one seminal RNA sample are shown.