Table 2. .
Mean ± SD Values of Peripapillary RNFL Thickness With AUC Curves and Sensitivities at Fixed Specificities for Discriminating Between Preperimetric Glaucoma and Control Groups
|
RNFL Thickness Parameter |
Preperimetric Glaucoma, n
= 48 |
Control, n
= 94 |
P
Value* |
AUC (SE) |
Sensitivity at 95% Specificity, % |
Sensitivity at 80% Specificity, % |
| Average and quadrants | ||||||
| Average | 86.0 ± 7.6 | 99.5 ± 8.2 | <0.001 | 0.89 (0.03) | 70.8 | 79.2 |
| Inferior hemisphere | 85.7 ± 8.3 | 100.1 ± 9.0 | <0.001 | 0.87 (0.03) | 64.6 | 75.0 |
| Inferior quadrant | 104.9 ± 12.1 | 124.5 ± 13.5 | <0.001 | 0.85 (0.03) | 50.0 | 75.0 |
| Superior hemisphere | 86.3 ± 8.7 | 98.8 ± 9.4 | <0.001 | 0.83 (0.03) | 47.9 | 77.1 |
| Superior quadrant | 100.4 ± 11.0 | 116.0 ± 13.8 | <0.001 | 0.81 (0.04) | 43.8 | 53.2 |
| Nasal quadrant | 69.2 ± 11.5 | 78.6 ± 8.5 | <0.001 | 0.75 (0.04) | 45.8 | 58.3 |
| Temporal quadrant | 69.6 ± 9.8 | 78.7 ± 10.3 | <0.001 | 0.73 (0.04) | 29.2 | 45.8 |
| 45° sectors | ||||||
| IT | 111.4 ± 18.1 | 136.4 ± 17.2 | <0.001 | 0.83 (0.03) | 43.8 | 68.8 |
| ST | 106.7 ± 14.5 | 127.5 ± 16.8 | <0.001 | 0.81 (0.03) | 45.8 | 68.8 |
| NU | 73.2 ± 12.0 | 82.8 ± 9.9 | <0.001 | 0.74 (0.04) | 33.3 | 62.5 |
| NL | 65.2 ± 12.3 | 74.4 ± 9.0 | <0.001 | 0.73 (0.04) | 43.8 | 52.1 |
| IN | 98.5 ± 14.4 | 112.6 ± 18.6 | <0.001 | 0.72 (0.04) | 20.8 | 52.1 |
| TU | 71.3 ± 10.8 | 80.4 ± 11.5 | <0.001 | 0.72 (0.04) | 16.7 | 52.1 |
| TL | 67.9 ± 10.7 | 77.0 ± 11.8 | <0.001 | 0.71 (0.04) | 22.9 | 37.5 |
| SN | 94.1 ± 14.3 | 104.6 ± 14.5 | <0.001 | 0.70 (0.04) | 33.3 | 54.2 |
| 22.5° sectors | ||||||
| IT1 | 119.6 ± 18.4 | 145.4 ± 18.9 | <0.001 | 0.82 (0.03) | 41.7 | 64.6 |
| ST2 | 105.0 ± 19.0 | 129.2 ± 18.7 | <0.001 | 0.81 (0.04) | 41.7 | 64.6 |
| TU2 | 77.6 ± 11.9 | 91.3 ± 14.7 | <0.001 | 0.77 (0.04) | 39.6 | 60.4 |
| IT2 | 103.1 ± 22.3 | 127.4 ± 23.0 | <0.001 | 0.77 (0.04) | 31.9 | 60.4 |
| NU1 | 64.1 ± 11.1 | 72.6 ± 8.1 | <0.001 | 0.74 (0.05) | 39.6 | 62.5 |
| NU2 | 82.2 ± 14.4 | 93.0 ± 13.7 | <0.001 | 0.73 (0.04) | 27.1 | 58.3 |
| NL2 | 69.2 ± 14.2 | 79.0 ± 11.0 | <0.001 | 0.73 (0.04) | 20.8 | 54.2 |
| NL1 | 61.2 ± 11.7 | 69.8 ± 8.7 | <0.001 | 0.72 (0.05) | 33.3 | 52.1 |
| TL2 | 72.5 ± 12.3 | 84.6 ± 15.9 | <0.001 | 0.72 (0.04) | 25.0 | 45.8 |
| ST1 | 108.4 ± 17.2 | 125.7 ± 22.8 | <0.001 | 0.72 (0.04) | 12.5 | 43.8 |
| IN1 | 104.8 ± 17.2 | 121.5 ± 22.4 | <0.001 | 0.71 (0.04) | 14.6 | 50.0 |
| SN2 | 96.5 ± 15.4 | 107.3 ± 15.8 | 0.001 | 0.69 (0.05) | 25.0 | 43.8 |
| SN1 | 91.8 ± 16.1 | 101.9 ± 16.2 | 0.002 | 0.68 (0.05) | 27.1 | 54.2 |
| IN2 | 92.1 ± 14.2 | 103.6 ± 17.2 | <0.001 | 0.68 (0.05) | 23.4 | 39.6 |
| TL1 | 63.3 ± 10.9 | 69.4 ± 10.9 | 0.003 | 0.65 (0.05) | 18.8 | 39.6 |
| TU1 | 65.0 ± 11.6 | 69.5 ± 10.9 | 0.035 | 0.59 (0.05) | 22.9 | 25.0 |
IT, inferotemporal; ST, superotemporal; NL, lower nasal; NU, upper nasal; IN, inferonasal; SN, superonasal; TL, lower temporal; TU, upper temporal.
*
For comparison of mean values of peripapillary retinal nerve fiber layer parameters between preperimetric glaucoma and control groups.