Table 4. .
Mean ± SD Values of Macular Parameters With AUC Curves and Sensitivities at Fixed Specificities for Discriminating Between Preperimetric Glaucoma and Control Groups
|
Macular Parameters |
Preperimetric Glaucoma, n
= 48 |
Control, n
= 94 |
P
Value* |
AUC (SE) |
Sensitivity at 95% Specificity, % |
Sensitivity at 80% Specificity, % |
| GCC parameters | ||||||
| Average thickness, μm | 83.6 ± 7.2 | 91.2 ± 6.6 | <0.001 | 0.79 (0.04) | 43.8 | 58.3 |
| Inferior thickness, μm | 83.0 ± 7.8 | 91.3 ± 6.8 | <0.001 | 0.79 (0.05) | 31.3 | 66.7 |
| Superior thickness, μm | 84.1 ± 7.5 | 91.1 ± 6.9 | <0.001 | 0.76 (0.05) | 31.3 | 62.5 |
| Root mean square, % | 0.10 ± 0.03 | 0.08 ± 0.02 | <0.001 | 0.67 (0.05) | 12.5 | 41.7 |
| Global loss volume, % | 11.3 ± 8.5 | 6.3 ± 5.1 | 0.002 | 0.65 (0.06) | 33.3 | 58.3 |
| Focal loss volume, % | 1.9 ± 2.0 | 1.00 ± 1.2 | 0.011 | 0.59 (0.06) | 14.6 | 43.8 |
| S-I thickness, μm | 1.1 ± 5.4 | −0.2 ± 3.6 | 0.148 | 0.55 (0.05) | 14.6 | 33.3 |
| Full retinal parameters | ||||||
| Inferior thickness, μm | 250.4 ± 11.9 | 258.3 ± 13.6 | 0.004 | 0.70 (0.06) | 8.3 | 45.8 |
| Average thickness, μm | 252.5 ± 11.7 | 260.2 ± 13.9 | 0.006 | 0.69 (0.06) | 6.3 | 35.4 |
| Superior thickness, μm | 254.7 ± 12.3 | 262.1 ± 14.7 | 0.011 | 0.67 (0.06) | 8.3 | 31.3 |
| S-I thickness, μm | 4.3 ± 5.7 | 3.8 ± 4.8 | 0.637 | 0.53 (0.05) | 12.5 | 31.3 |
| Outer retinal parameters | ||||||
| S-I thickness, μm | 3.2 ± 2.8 | 4.0 ± 2.8 | 0.151 | 0.58 (0.05) | 10.4 | 37.5 |
| Superior thickness, μm | 170.6 ± 7.8 | 171.0 ± 10.5 | 0.828 | 0.53 (0.06) | 0.0 | 12.5 |
| Average thickness, μm | 169.0 ± 7.6 | 169.0 ± 10.0 | 0.994 | 0.52 (0.06) | 0.0 | 12.5 |
| Inferior thickness, μm | 167.4 ± 7.8 | 166.0 ± 9.8 | 0.830 | 0.50 (0.06) | 0.0 | 12.5 |
S-I, superior minus inferior.
*
For comparison of mean values of macular parameters between preperimetric glaucoma and control groups.