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The effect of IA channel blocker 4-AP on AP firing pattern. (A) The morphology of repetitive APs recorded in hiPS cell-derived neurons (upper) is shaped by the application of 5 mM 4-AP (lower). (B) 4-AP (5 mM) decreases the firing frequency of repetitive APs (left), but greatly increases their half widths (right). *P<0.05, comparing the correlated groups as indicated. n=5 in each group.
