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Histograms of population V3 sequencing g2p fpr (%) distribution, stratified by Trofile-determined tropisms (gray, R5; black, non-R5). (a) Subtype B (N=1859) from MOTIVATE/1029. (b) Non-B subtypes (N=260). Vertical dotted lines indicate optimized cutpoint [5.75% false-positive rate (fpr)] based on MOTIVATE-1 and −2 trials virological outcome. *fpr (%) are plotted in log scale and labeled in linear scale.
