Electrophysiological parameters of the neurons derived with or without DA. (A) Representative traces of 3 cells in current clamp exposed to 0, 10, or 100 μM DA. Vertical scale bar=20 mV, horizontal scale bar=20 ms. (B) Corresponding traces of the same 3 cells in voltage clamp. Vertical scale bar=200 pA, horizontal scale bar=20 ms. (C) Peak Na+ current, peak K+ current, input resistance, and resting membrane potential, for 0, 10, and 100 μM DA-treated hESCs. Cells were patched between days 22 and 38 of the protocol. n=30, 18, and 8 for 0, 10, and 100 μM, respectively. Error bars=SEM.