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. Author manuscript; available in PMC: 2013 Sep 5.
Published in final edited form as: Eur J Pharmacol. 2012 Jul 11;690(0):149–157. doi: 10.1016/j.ejphar.2012.07.003

Figure 5.

Figure 5

Effect of isoflurane on rate of ATP production and ATP hydrolysis. (A) Summary data showing the effect of increasing isoflurane concentrations on ATP synthesis with substrates for complex I or II in isolated mitochondria. (B) Effect of isoflurane on ATP hydrolysis measured as phosphate release in submitochondrial particles. Oligomycin (Oligo) was used as a positive control. PM = pyruvate/malate. All values are means±S.D., n=6, *P<0.05 versus 0 mM isoflurane.