Skip to main content
. Author manuscript; available in PMC: 2013 May 14.
Published in final edited form as: J Allergy Clin Immunol. 2010 Apr;125(4):778–787. doi: 10.1016/j.jaci.2010.02.018

Figure 2.

Figure 2

Schematic morphology of the spleen (A) and the germinal center reaction (B). The white pulp consists of a central artery surrounded by T cells; the marginal zone and the follicles. Antigen-specific B cells and T cells interact at the border of the follicle. The B cells differentiate into centroblasts and undergo clonal expansion in the germinal center dark zone.