Figure 7.

H-L-g7xK and K/BxN mice are protected from bleomycin lung injury. (A) Weight loss (%) was compared with initial weight after bleomycin was instilled intratracheally on Day 0 (n = 5 mice per group). (B) Fibrosis was scored by a blinded observer according to the technique described in Materials and Methods. (C) The extent of lymphocytic infiltrates was scored as described in Figure 5C. (D) Masson trichrome–stained (Tri) and hematoxylin and eosin–stained (H&E) lungs from untreated and bleomycin-treated (Bleo) mice on Day 21. Arrows represent areas scored as fibrosis. Magnification, ×4.