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Serial FLASH images pre- and post-injection of Gd-DTPA (top) and EP-2104R (bottom) show transient tumor core enhancement following contrast administration. The tumor periphery remains enhanced at least 90 min after EP-2104R injection. Low resolution images A, B, E and F. High resolution images C, D, G and H. Arrow in image H indicates the tumor core and arrowhead indicates triangular enhanced region in tumor periphery.
