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. Author manuscript; available in PMC: 2013 May 14.
Published in final edited form as: Mol Carcinog. 2010 Apr;49(4):363–373. doi: 10.1002/mc.20609

Figure 4. Response of wildtype and sdc-1 mice after 3 weekly treatments to topical TPA.

Figure 4

Shown are 3 timepoints after the last application of TPA. A. BrdU incorporation (2 hours IP), n=6. B. MPO activity in 8mm skin punch biopsies, n=6 C. Unfixed frozen sections were used to localize α3 integrin and TGFβ1. White dashed white lines demarcate the apical margin of the epidermis and arrows indicate TGFβ1 localization within the epidermis. D. Total epidermal and dermal TGFβ1 levels determined by ELISA assay at 3 timepoints after the third TPA treatment or 7 days after the second TPA treatment, n=6. Bar in C = 15 μm.