Table 1.
Minor allele frequencies (MAF) and P-values for Hardy-Weinberg (HW) and association tests for SNPs with P<0.05 in the Swedish population
| Gene | SNP ID | Chromosome position | Study MAF | HW test |
Association test† |
OR |
95% CI |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Allele | Genotype | Lower | Upper | |||||||||
|
IL10 |
rs3021094 |
1 |
206944952 |
0.092 |
0.16 |
0.020 |
(0.72) |
0.078 |
(0.92) |
1.6 |
1.1 |
2.2 |
|
NOD1 |
rs4363092 |
7 |
30503938 |
0.18 |
0.36 |
0.050 |
(0.72) |
0.045 |
(0.92) |
1.3 |
1.0 |
1.8 |
|
NOD1 |
rs4720003 |
7 |
30508992 |
0.18 |
0.37 |
0.041 |
(0.72) |
0.033 |
(0.92) |
1.3 |
1.0 |
1.8 |
|
NPSR1 |
rs2022142 |
7 |
34705950 |
0.10 |
1.0 |
0.035 |
(0.72) |
0.056 |
(0.92) |
1.5 |
1.0 |
2.1 |
|
NPSR1 |
rs1379925 |
7 |
34715128 |
0.091 |
1.0 |
0.021 |
(0.72) |
0.031 |
(0.92) |
1.6 |
1.1 |
2.3 |
|
NPSR1 |
rs1379923 |
7 |
34717238 |
0.25 |
0.41 |
0.045 |
(0.72) |
0.11 |
(0.92) |
0.8 |
0.6 |
1.0 |
|
NPSR1 |
rs17788770 |
7 |
34793991 |
0.10 |
0.68 |
0.083 |
(0.72) |
0.035 |
(0.92) |
0.7 |
0.5 |
1.0 |
|
NPSR1 |
rs17789834 |
7 |
34871328 |
0.19 |
0.32 |
0.011 |
(0.70) |
0.039 |
(0.92) |
1.4 |
1.1 |
1.9 |
|
SCGB1A1 |
rs11231085 |
11 |
62190448 |
0.36 |
0.74 |
0.037 |
(0.72) |
0.0049 |
(0.58) |
1.3 |
1.0 |
1.6 |
|
CCL5 |
rs1065341 |
17 |
34198593 |
0.040 |
0.41 |
0.027 |
(0.72) |
0.085 |
(0.92) |
1.8 |
1.1 |
3.2 |
|
CCL5 |
rs3817655 |
17 |
34199641 |
0.17 |
0.12 |
0.0028 |
(0.29) |
0.0088 |
(0.58) |
1.6 |
1.2 |
2.1 |
|
CCL5 |
rs2107538 |
17 |
34207780 |
0.17 |
0.27 |
0.0021 |
(0.29) |
0.0069 |
(0.58) |
1.6 |
1.2 |
2.1 |
| TBXA2R | rs3786989 | 19 | 3604004 | 0.93 | 0.25 | 0.038 | (0.72) | 0.086 | (0.92) | 0.6 | 0.4 | 1.0 |
†Association with AR estimated using a χ2-homogeneity test with Q-values in parenthesis calculated according to Storey (2002).
Odds ratio (OR) and 95% confidence interval were estimated by using the most common allele as the referent and are reported for each minor allele.