Table 3.
Psychosocial risk factors by probable HIV dementia (PHD)
| Number in study (N,%) | Probable HIV dementia (n,%) | Unadjusted OR (95% CI) | Adjusted OR§ (95% CI) | |
|---|---|---|---|---|
|
Social Support |
|
|
P=0.644 |
P=0.179 |
| Low |
188 (30.4) |
123 (65.4) |
1.09 (0.76-1.56) |
1.1. (0.76-1.59) |
| High |
430 (69.6) |
273 (63.5) |
1 |
1 |
|
Negative life events |
|
|
P<0.001 |
P<0.001 |
| 1-5 events |
350 (56.6) |
199 (56.9) |
1 |
1 |
| 6-10 events |
191 (43.7) |
138 (72.8) |
2.03 (1.38-2.97) |
2.14 (1.45-3.15) |
| 11 + |
77 (12.5) |
58 (74.3) |
2.32 (1.32-4.05) |
2.35 (1.33-4.13) |
|
Stress Score index |
|
|
P<0.001 |
P<0.001 |
| Low (score 0) |
164 (26.5) |
77 (46.9) |
1 |
1 |
| Medium (score 1–10) |
323 (52.3) |
222 (68.7) |
2.48 (1.69-3.65) |
2.55 (1.73-3.77) |
| High (score>10) |
131 (21.2) |
97 (74.0) |
3.22 (1.96-5.30) |
3.29 (1.99-5.45) |
|
Negative Coping Style index |
|
|
P=0.554 |
P=0.606 |
| Low |
101 (16.3) |
81 (80.2) |
1 |
1 |
| Medium |
322 (52.1) |
160 (52.5) |
0.27 (0.16-0.47) |
0.26 (0.15-0.44) |
| High |
195 (31.6) |
146 (74.9) |
0.74 (0.41-1.32) |
0.71 (0.39-1.28) |
|
Psychosocial Impairment |
|
|
P=<0.001 |
P=<0.001 |
| Present | 318 (51.5) | 176 (55.3) | 0.45 (0.32-0.63) | 0.45 (0.32-0.64) |
Note: § Adjusted for age and sex.