Skip to main content
. 2013 May 14;8(5):e63809. doi: 10.1371/journal.pone.0063809

Figure 2. Mice treated with topical vitamin E have increased numbers of p53-positive foci.

Figure 2

Dorsal, tumor-free skin sections were examined via immunohistochemistry with an antibody detecting both wild type and mutant p53. Representative images of skin from mice treated with (A) vehicle, (B) C E Ferulic, and (C) vitamin E for 15 weeks after 10 weeks of UVB exposure. (D) The average number of p53-positive foci per field of view was significantly higher in mice treated with vitamin E compared to vehicle-treated mice (*p = 0.0216).