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. 2013 May 14;8(5):e64251. doi: 10.1371/journal.pone.0064251

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© 2013 Cisse et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Repartition of litters in relation with the litter size. Results are expressed in percentage. (B) Body weight of pups at birth in relation with the litter size. (C) Classification of pups in relation with the birth weight in different categories: small for gestational age (SGA), appropriate for gestational age (AGA) and large for gestational age (LGA). (D) Percentage of LGA pups in relation with the litter size. The effect of treatment was analyzed by one-way ANOVA followed by the Bonferroni posthoc test. ***p<0.001 indicates the significant difference between controls and N-STZ. C, control; N-STZ, nicotinamide-streptozotocin.