Figure 3. The 4q32A>C mutation is associated with reduced levels of enhancer markers.

ChIP assays of lymphoblastoid cell lines established from a control individual (4q32-A/A) and a PTC patient in the family (4q32-A/C). Antibodies against H3K4me1, P300, and MED1 were used in the assays. **: p-value<0.01; *: p-value<0.05. Error bars represent ±SD of at least three independent experiments.