Table 2. Significant known and novel common insertion sites.

Chromosome	Start (bp)	End (bp)	Curated Target Gene	Tumors with Insertion	CGC	Amplified in Cell Lines (CONAN)	Deleted in Cell Lines	COSMIC (% mutated of samples tested)
Known CISs
chr15	98520001	98712001	Wnt1	270	N	3	0	0
chr7	151923001	152121001	Fgf3	195	N	28	0	0
chr19	45606001	45867001	Fgf8	135	N	0	0	0
chr11	59004001	59175001	Wnt3a	84	N	5	0	1%
chr11	103557001	103779001	Wnt3	59	N	1	0	0
chr7	137232001	137505001	Fgfr2	51	Y	5	0	3%
chr15	42954001	43134001	Rspo2	48	N	6	0	2%
chr18	4275001	4395001	Map3k8	30	N	0	0	0
chrX	138084001	138234001	Irs4	23	N	1	1	1%
chr10	29211001	29361001	Rspo3	25	N	0	0	NA
chr7	149778001	149895001	Igf2	19	N	0	0	0
chr2	10242001	10353001	Sfmbt2	17	N	0	0	0
chr5	75501001	75594001	Pdgfra	14	Y	5	0	7%
chrX	7464001	7554001	Eras	13	N	0	0	1%
chr18	61179001	61236001	Pdgfrb	7	Y	1	0	1%
chr10	29490001	29529001	Rspo3 enhancer	6	N	0	0	NA
chr6	127188001	127203001	Fgf6/Fgf23	4	N	3 - Fgf6/4 - Fgf23	0	0.5% - Fgf6/1% Fgf23
chr13	119487001	119520001	Fgf10	5	N	14	0	1%
New CISs
chr8	26397001	26667001	Fgfr1 1	30	Y	5	0	1%
chr18	36621001	36714001	Hbegf	15	N	0	0	0
chr10	20820001	20898001	Myb 2	9	Y	5	0	0
chr11	121536001	121599001	Metrnl/Ptchd3	8	N	2	0	0% - Metrnl/Ptchd3
chr15	74901001	74943001	Reg. Feat	6	N	NA	NA	NA
chr6	103575001	103623001	Chl1	6	N	0	0	1%
chr4	124671001	124716001	Rspo1	6	N	3	0	0
chr3	97782001	97821001	Notch2	6	Y	2	0	2%
chr5	34044001	34068001	Fgfr3	5	Y	2	0	26%
chr11	3051001	3072001	Sfi1	5	N	0	0	1%
chr14	68478001	68511001	Dock5	5	N	0	2	4%
chr6	23181001	23217001	Fezf1	5	N	10	0	3%

This table gives an overview of the significant CISs and their potential target genes.

¹Although Fgfr1 has not been found as a common insertion site in [11], the authors do mention finding one insertion near the gene.

²The Myb CIS is a merge of two overlapping CISs (upstream and downstream of the Myb gene).