Figure 4. Validation of proteomic results through immunoblotting and gene expressions for a subset of corresponding proteins.

CUS upregulates VDAC3, PHB2 and SLC25A5 gene expression levels, as indicated by the fold changes at the mRNA level (a). Similarly, we validated the stress regulation of VDAC3 & SNCB (2 identified proteins from the proteomic list), as observed in the immunoblot result (b).