Table 7. Calculations of Observed & Expected values, Variance, χ ² test in Case-Control study, dTDT and MH test.

	Case-Control study			dTDT				MH test
Structure		Case	Control	NT
				allele 1			allele 2	–
	# allele 1			T	allele 1	–
	# allele 2				allele 2		–
Total (N)				–
Observed (O)									*
Expected (E)
Variance
χ 2 test

Number of Cases (#cs) = 847; Number of Controls (#cn) = 552; f_cs: allele frequency in cases; f_cn: allele frequency in controls; T is short for Transmitted; NT is short for Non-Transmitted. b₂ = Σb_i and c₂ = Σc_i. Using either a ₁ or c ₁ in Case-Control study will give the same results.

^*equivalent to .