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. 2013 May 14;8(5):e62412. doi: 10.1371/journal.pone.0062412

Figure 1. Global host transcriptional response in the lungs of animals following aerosol exposure to virulent F. tularensis.

Figure 1

A. Number of transcripts that are differentially expressed (at least 2-fold difference in median expression level, p value 0.01) in the lungs of animals exposed to FT SchuS4 at 4, 24 and 48 hrs post-exposure. Transcripts showing increased or decreased expression relative to control animals are shown in red and green bars, respectively. B. Hematoxylin and eosin stained lung tissue from animals exposed to FT SchuS4. Magnification 20x. C. Gene ontology analysis of approximately 400 transcripts induced by FT SchuS4 at 4 hrs demonstrating enrichment of specific functional groups.