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(A) The conversion of the 27 carbon cholesterol to primary and secondary 24 carbon bile acids by liver enzymes and the microbiome/gut flora is shown. Representative primary and secondary bile acids together with the orientation of the hydroxyls are indicated.
(B) Relative bile acid composition in the human (modified from Hofmann, 2010) and mouse bile acid pool (modified from Kerr et al., 2002).
