TABLE 4.
Description of reviewed published manuscripts reporting extracolonic findings for ovarian cancer.
| Author | Year | Country | Sample size | Age range | Mean/Median Age | Number of ECFa | Number of True Positives | False Positive Rate | Prevalence (per 1000) | PPV |
|---|---|---|---|---|---|---|---|---|---|---|
| Screening populations | ||||||||||
| Ginnerup Pederson B [33] | 2003 | Denmark | 35 | 33–78 | 61 | 1 | 0 | 2.9 | 0 | 0 |
| Gluecker TM [21] | 2003 | US | 255 | 41–80 | 64 | 6 | 0 | 2.4 | 0 | 0 |
| Chin M [23] | 2005 | Australia | 202 | 50–69 | 3 | 0 | 1.5 | 0 | 0 | |
| Pickhardt PJ [17] | 2008 | US | 1199 | 40–90 | 58 | 13 | 0 | 1.1 | 0 | 0 |
| Veerappan GR [18] | 2010 | US | 1002 | 59 | 5 | 0 | 0.5 | 0 | 0 | |
| Non-screening populations | ||||||||||
| Morrin MM | 1999 | US | 28 | 22–96 | 1 | NA | - | - | - | |
| Edwards JT [19] | 2001 | Australia | 53 | 65 | 3 | 0 | 5.7 | 0 | 0 | |
| Serracino-Inglott F [26] | 2004 | UK | 56 | 43–88 | 68 | 5 | 1 | 7.3 | 17.9 | 20.0 |
| Spreng A [22] | 2005 | Switzerland | 39 | 20–91 | 66 | 3 | 1 | 5.3 | 25.6 | 33.3 |
| Khan KY [24] | 2007 | UK | 134 | 62–81 | 74 | 5 | 0 | 3.7 | 0 | 0 |
| Tolan D [28] | 2007 | UK | 250 | 70–96 | 79.6 | 5 | 0 | 2.0 | 0 | 0 |
| Flicker MS [20] | 2008 | US | 238 | 26–89 | 61 | 3 | 1 | 0.8 | 4.2 | 33.3 |
| Roberts-Thomson IC [25] | 2008 | Australia | 110 | 25–85 | 60 | 3 | 0 | 2.7 | 0 | 0 |
| Yucel C [27] | 2008 | US | 26 | 60–87 | 71 | 1 | NA | - | - | - |
| Unknown/Mixed | ||||||||||
| Park SK [43] | 2009 | South Korea | 385 | 34–87 | 57.3 | 1 | NA | - | - | - |
a
ECF=extracolonic finding, PPV=positive predictive value, NA=not available, (-)=could not calculate; CI=confidence interval