Table 1.
Demographic and clinical characteristics of overall cohort and functional groups.
| Characteristic | Overall Cohort | Low function | Intermediate | High function |
|---|---|---|---|---|
| N=359 (%) | N=33 (%) | N=186 (%) | N=140 (%) | |
| Demographics | ||||
| Age, years | 52.1 (0.3) | 52.9 (0.8) | 52.2 (0.4) | 51.7 (0.5) |
| Female | 54 (15) | 8 (24) | 27 (15) | 19 (14) |
| Hispanic/Latino | 65 (18) | 7 (21) | 37 (20) | 21 (15) |
| Non-white | 94 (26) | 8 (24) | 48 (26) | 38 (27) |
| Current smoker | 123 (34) | 17 (52) | 71 (38) | 35 (25) |
| HIV Characteristics | ||||
| Current CD4+ T-cells/μL | 600 (16) | 579 (55) | 578 (22) | 634 (25) |
| Detectable HIV-1 RNA (≥ 48 copies/mL) | 18 (5) | 1 (3) | 8 (4) | 9 (6) |
| Comorbidities | ||||
| Diabetes | 37 (11) | 7 (21) | 23 (13) | 7 (5) |
| Hypertension | 148 (41) | 18 (55) | 81 (44) | 49 (35) |
| Cardiovascular disease | 34 (9) | 4 (12) | 24 (13) | 6 (4) |
| Chronic pain | 129 (37) | 22 (71) | 95 (52) | 12 (9) |
| Hepatitis B or C* | 89 (25) | 15 (45) | 47 (25) | 27 (19) |
| VACS Index Score | 10.7 (0.6) | 25.1 (2.9) | 9.9 (0.8) | 8.4 (0.8) |
| Number of Non-ART Medications | 4.7 (0.2) | 6.4 (0.6) | 5.2 (0.2) | 3.5 (0.2) |
| Clinical Outcomes | ||||
| Any hospitalization during prior 12 months | 77 (22) | 17 (52) | 40 (22) | 20 (14) |
| Fall† during prior 12 months | 109 (30) | 24 (73) | 66 (35) | 19 (14) |
Values are presented as frequency (percentage) or mean (standard error). Abbreviations: SE, standard error; VACS, Veterans Aging Cohort Study
*
positive hepatitis B virus surface antigen and/or positive hepatitis C virus antibody,
†
Fall was defined as unintentionally coming to rest on the ground or other lower level, not as a result of a major intrinsic event or external hazard