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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Pflugers Arch. 2013 Feb 9;465(5):655–667. doi: 10.1007/s00424-013-1227-y

Fig. 1. Cellular pathway analysis of predicted miRNA target genes.

Fig. 1

Putative miRNA target gene cellular pathways altered by age were generated using the software program DIANA-miRpath [67]. Mature miRNA expression levels were analyzed from the hippocampus of female Fisher 344 rats at 3 and 18 mo. of age. All animals were ovariectomized 7 days prior to tissue collection and total RNA isolation. miRNA expression levels were analyzed using a rat microRNA microarray platform (LC Biosciences, Sanger 18.0 miRbase probes). Loyola University Institutional Animal Care and Use Committee approved all animal experiments.