Table 2.

Family history variables as a risk factor for predicting conversion from BD-NOS to BD-I or BD-II in children (N=27).

	Fisher's exact p-value 1-tailed/2-tailed	OR(CI)	RR	Power	N needed for power of.80
≥ 1 First-degree relative
BD Dx or Sx	0.17/0.24	3.14 (0.59–16.85)	2.19	0.39	92
BD Dx only	0.55/1.00	1.26 (0.25–6.36)	1.16	0.11	2473
Loaded
Depression Dx or Sx	0.40/0.68	1.78 (0.33–9.55)	1.47	0.18	355
Depression Dx only	0.13/0.22	3.67 (0.66–20.19)	2.34	0.45	70
Multigenerational
Depression Dx or Sx	0.64/1.00	1.09 (0.20–6.01)	1.06	0.10	15,456
Depression Dx only	0.30/0.43	2.25 (0.42–12.09)	1.72	0.25	177

BD=bipolar disorder; OR=odds ratio; RR=relative risk; Dx=diagnosis; Sx=symptoms.