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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2013 Feb 14;60:10.1016/j.freeradbiomed.2013.02.003. doi: 10.1016/j.freeradbiomed.2013.02.003

Table 2.

Hematological chemotherapeutic sensitivity in the WEHI7.2 cells and the WEHI7.2 variants.

Cell Variant Cyclophosphamide EC50 (mM)a Doxorubicin EC50 (nM)a Doxorubicin EC90 (nM)a Vincristine EC50 (nM)a Vincristine EC90 (nM)a Dexamethasone (% apoptosis)b
WEHI7.2# 1.82 ± 0.03 8.60 ± 0.58 23.74 ± 0.65 2.37 ± 0.17 4.26 ± 0.34 23.79 ± 1.30
200R# 5.71 ± 0.18* 11.40 ± 1.11 28.66 ± 0.72* 9.01 ± 3.90 48.43 ± 3.53* 10.16 ± 0.28*
Hb12 6.34 ± 0.39* 23.36 ± 0.84* 63.43 ± 2.80* 2.51 ± 0.30*
a

Values represent the mean ± SEM (n ≥ 3).

b

Values are the mean percent apoptosis after a 24h treatment with 1 μM dexamethasone corrected for % apoptosis in vehicle-treated cells (n = 3).

#

These data have been previously published (6).

*

denotes significantly different from WEHI7.2 values (p ≤ 0.05).