Table 2.
Cell Variant | Cyclophosphamide EC50 (mM)a | Doxorubicin EC50 (nM)a | Doxorubicin EC90 (nM)a | Vincristine EC50 (nM)a | Vincristine EC90 (nM)a | Dexamethasone (% apoptosis)b |
---|---|---|---|---|---|---|
WEHI7.2# | 1.82 ± 0.03 | 8.60 ± 0.58 | 23.74 ± 0.65 | 2.37 ± 0.17 | 4.26 ± 0.34 | 23.79 ± 1.30 |
200R# | 5.71 ± 0.18* | 11.40 ± 1.11 | 28.66 ± 0.72* | 9.01 ± 3.90 | 48.43 ± 3.53* | 10.16 ± 0.28* |
Hb12 | 6.34 ± 0.39* | 23.36 ± 0.84* | 63.43 ± 2.80* | 2.51 ± 0.30* |
Values represent the mean ± SEM (n ≥ 3).
Values are the mean percent apoptosis after a 24h treatment with 1 μM dexamethasone corrected for % apoptosis in vehicle-treated cells (n = 3).
These data have been previously published (6).
denotes significantly different from WEHI7.2 values (p ≤ 0.05).