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Mitophagy receptors in yeast and mammals. The yeast mitophagy receptor Atg32 interacts with the Atg8 and Atg11 proteins in order to completely remove damaged mitochondria. An interaction between LC3/GABARAP proteins and the mitophagy receptors, Nix and Bnip3 is not sufficient for fully functional mitophagy in the mammalian system; an additional binding partner(s) needs to be defined.
