Fig. S3.

Ischaemic zone size was not affected by ivabradine: (A) Heart at the end of an ischaemia-reperfusion experiment following addition of Evans Blue into the perfusate, with the non-ischaemic zone stained blue, and the ischaemic zone unstained. (B) The mass of the ischaemic zone expressed as percentage of total ventricular mass was not different between control and ivabradine groups. (C) The percentage coronary flow reduction, a surrogate of ischaemic zone size, was also not different between groups. (D) Coronary flow recovery with reperfusion was similar between groups (CFR: coronary flow rate).