. Author manuscript; available in PMC: 2013 May 15.

Published in final edited form as: J Mol Biol. 2012 Feb 17;418(0):10.1016/j.jmb.2012.02.010. doi: 10.1016/j.jmb.2012.02.010

Table 1.

Summary of extents of fusion and contents release of vesicles composed of various phospholipids and cholesterol by the HIV gp41 fusion domain and its secondary structure in bilayers of corresponding lipid compositions.

Lipid Composition	% Negative Lipids	% Cholesterol	% Lipid Mixing	% Contents Mixing/Release	Predominant Secondary Structure
POPC:POPG (4:1)	20	0	55	22	α-helix
		10	60	33	α-helix
		20	60	70	α-helix
		30	70		β-structure
POPC:POPS (4:1)	20	0	15	4	α-helix
		10	60		α-helix
		20	65	63	α-helix
		30	80		β-structure
POPC:POPS: PI (12:2:1)	20	0	30	27	α-helix
		33	70	62	β-structure
POPC:POPS: SM:POPS:PI (20:5:2:2:1)	10	0	23	45	α-helix
		33	55	68	β-structure