Table 2.

Results of a multivariate analysis of the pathological characteristics associated with invasion in ductal carcinoma in situ (DCIS).

DCIS	Variable	OR	95% CI	Coefficient	SE	p-value
Total	ER/PR-negative	4.67	1.87–11.70	1.54	0.47	0.0010
	HER2-positive	0.39	0.17–0.93	−0.93	0.44	0.0333
	CK 5/6-positive	0.22	0.10–0.48	−1.5	0.39	0.0001
Low-grade	CK 5/6-positive	0.22	0.09–057	−1.5	0.49	0.0019
High-grade	Triple-positive	0.09	0.02–0.51	−2.37	0.87	0.006
	CK 5/6-positive	0.28	0.09–0.93	−1.24	0.59	0.04

ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor 2; CK 5/6: cytokeratin 5/6; OR: odds ratio; SE: standard error.