Table 1.
Seven cases of steroid-sensitive nephrotic syndrome from three families.
Family | 1 | 2(8) | 3 | ||||
Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Sex (M/F) | F | M | M | M | M | M | M |
Age at onset (years) | 8 | 5 | 13 | 15 | 35 | 2.8 | 2.9 |
Interval of onset (months) | ? | 49 | ? | 36 | 96 | ? | 2 |
Hematuria | No | No | No | No | No | No | No |
Hypertension | No | No | No | No | Yes | No | No |
Renal function | Normal | Normal | Normal | Normal | Normal | Normal | Normal |
Immunosuppressant | Pre+CTX | Pre+MMF | Pre | Pre | Pre | Pre | Pre |
Days to remission | 13 | 12 | Unknown | 7 | Unknown | 10 | 15 |
Renal pathology | MCD | MCD | MCD | MCD | MsPGN | No | No |
Number of relapses | 3 | 5 | 0 | 4 | 0 | 1 | 0 |
Pre: prednisone, CTX: cyclophosphamide, MMF: mycophenolate mofetil, MCD: minimal change disease, MsPGN: mesangial proliferative glomerulonephritis, F: female, M: male.