Table 2.
Immunohistochemical profile of high-grade DCIS (pure or associated with invasive mammary carcinoma).
| Pure DCIS | DCIS + IMC | ||
| Phenotype | N (%) | N (%) | p-value*) |
| Luminal A | 24 (57.1%) | 46 (58.2%) | 0.264 |
| Luminal B | 05 (11.9%) | 10 (12.7%) | |
| HER2 | 07 (16.7%) | 06 (7.6%) | |
| Basal-like | 00 (0%) | 06 (7.6%) | |
| “Not classified” | 06 (14.3%) | 11 (13.9%) | |
| TOTAL | 42 (100%) | 79 (100%) |
DCIS = ductal carcinoma in situ; IMC = invasive mammary carcinoma
Luminal A: ER+/HER2-; Luminal B: ER+/HER2+; HER2: ER-/HER2+; Basal: ER-/HER2-/EGFR+ and/or CK5+; “Not classified”: ER-/HER2-/EGFR-/CK5-.
p = significance level.
*
= Exact Pearson's chi-square test; refers to in situ component (pure or associated with invasive carcinoma).