Table 1.

Reversal of multidrug-resistance in the colon cancer cell line HCT-8/VCR by curcumin (mean ± SD, n = 3).

Drugs	IC50 (μg/ml)		RF
	HCT-8/VCR	HCT-8/VCR+curcumin
VCR	62.3±1.2	13.6±0.9*)	4.6
DDP	47.9±3.6	16.1±1.7*)	3.0
5-FU	13.4±1.3	8.3±0.8*)	1.6
HCPT	34.2±2.1	29.7±1.8*)	1.2

^*p<0.05 vs. HCT-8/VCR, RF  =  reversal fold.