Figure 5.

Patient 2’s non-invasive dEEG localization of a typical (right frontal) spike. (A) Topographic map of scalp potentials at peak of spike (which is used for spike classification). Orientation is top looking down with the nose at the top; red = positive, blue = negative, white = zero. (B) Waveforms of EEG from all channels (top row), source waveforms from all 2272 sources (second row), source waveform from dipole that shows maximal activity at 50% of spike peak (third row, blue trace) and source waveform from dipole at a distance from maximal location (third row magenta trace), and the frequency spectra of the blue source waveforms (third row) shown in forth row. Note that the dipole location of the blue trace is in the right temporal lobe. In (B), each column represents 1 s of data from a 3-s segment. Middle column represent data centered on the spike peak. (C) Electrical source localization with the patient’s individual electrical head model. Left: scalp potential reconstructed from the source estimate (at 50% of spike peak). Right: partially inflated brain illustrating the dominant source associated with the data illustrated in left figure [location of dipole described by blue trace in (B), third row]. Data was thresholded to only show top 5% activity.