Table 4.
Summary results of Cox proportional hazards (CPH) model evaluating the effect of covariates on overall survival (OS) and cancer specific survival (CSS). (HR is Hazard ratio, MPBC is micropapillary bladder cancer, and UC is traditional urothelial carcinoma).
| CPH Model including those with MPBC and UC | CPH Model including only those with MPBC | |||||||
|---|---|---|---|---|---|---|---|---|
| OS | CSS | OS | CSS | |||||
| Covariate | HR | p value | HR | p value | HR | p value | HR | p value |
| Stage | 3.30 - T2 vs Ta/T1/Tis 1.38 - T3/T4 vs T2 1.76 - N+ vs T3/T4 2.23 - M+ vs N+ |
<0.0001 | 6.05 - T2 vs Ta/T1/Tis 1.50 - T3/T4 vs T2 1.93 - N+ vs T3/T4 2.34 - M+ vs N+ |
<0.0001 | 3.05 - T2 vs Ta/T1/Tis 2.78 - T3/T4 vs T2 0.97 - N+ vs T3/T4 1.07 - M+ vs N+ |
0.0007 | 2.54 - T2 vs Ta/T1/Tis 5.97 - T3/T4 vs T2 1.08 - N+ vs T3/T4 1.15 - M+ vs N+ |
0.0008 |
|
Grade (High vs Low) |
1.56 | <0.0001 | 2.93 | <0.0001 | 0.59 | 0.3169 | 0.35 | 0.1878 |
|
Age (per yr) |
1.07 | <0.0001 | 1.05 | <0.0001 | 1.06 | 0.0001 | 1.03 | 0.1290 |
|
Race (Black vs not) |
1.43 | <0.0001 | 1.61 | <0.0001 | 0.65 | 0.4990 | 0.42 | 0.3978 |
|
Sex (Female vs Male) |
0.93 | 0.0322 | 1.14 | 0.0099 | 1.07 | 0.8653 | 1.15 | 0.7965 |
|
Definitive tx vs not |
0.94 | 0.2709 | 0.90 | 0.0933 | 0.36 | 0.0584 | 0.43 | 0.1947 |
| MPBC vs TCC | 1.04 | 0.7966 | 0.80 | 0.2417 | ||||