Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Interactions of the c-kit dimer. When the dimerization of the c-kit is induced by SCF, D1-D3 remains unchanged, whereas D4 and D5 become reoriented to reach each other by overcoming the electrostatic repulsion. Left structure shows the model of c-kit dimer with two free c-kit molecules. Right structure shows that the D4-D4 and D5-D5 domains are in close proximity in actual SCF-induced c-kit dimer.
