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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Nov 16;1831(2):10.1016/j.bbalip.2012.10.010. doi: 10.1016/j.bbalip.2012.10.010

Fig. 2.

Fig. 2

Conformational changes induced in FAPP2-C212 by vesicles with differing lipid composition assessed by far-UV and near-UV CD. FAPP2-C212+no vesicles (black); +POPC vesicles (green); +POPC/POPA (9:1) vesicles (orange); +POPC/POPA/18:1-GalCer (8:1:1) vesicles (purple). A) Far-UV CD spectra are presented in units of molar ellipticity per residue. Dramatic change in the secondary structure of FAPP2-C212 upon interaction with POPC, POPC/POPA, and POPC/POPA/18:1-GalCer vesicles is not observed. B) Temperature dependence of molar ellipticity at 222 nm (derivative plot). C) Near-UV CD spectra. Signal response from Tyr and Trp in FAPP2-C212 is not clearly discernible and changes induced by POPC, POPC/POPA, and POPC/POPA/18:1-GalCer vesicles are minor.