Figure 5.

The absolute cryptococcal antigen (CRAG)–specific cytokine–producing, interferon γ (IFN-γ)–producing, tumor necrosis factor α (TNF-α)–producing and macrophage inflammatory protein 1α (MIP-1α)–producing CD4⁺ T-cell counts at baseline in subjects who survived and subjects who died. Absolute numbers of antigen-specific CD4⁺ T cells were calculated by multiplying the proportion of cytokine-positive CD4⁺ T cells by the total CD4⁺ T-cell count. Responses are shown according to 2-week mortality outcome. Statistical comparisons were made using the Mann–Whitney U test.