Table 1.
Experimental Group | AB103 Dose,a mg/kg | LVSΔguaB Dose,b CFU | F. tularensis Inoculum, CFU | Survival Ratio | Time(s) to Death, d |
---|---|---|---|---|---|
1 (5 mice) | None | None | 1 × 105 | 0/5 | 5, 5, 6, 7, and 7 |
2 (5 mice) | None | 1 × 107 | 1 × 105 | 5/5 | NA |
3 (5 mice) | 0.5 | 1 × 107 | 1 × 105 | 5/5 | NA |
4 (5 mice) | 5 | 1 × 107 | 1 × 105 | 5/5 | NA |
Abbreviations: CFU, colony forming units; F. tularensis, Francisella tularensis; NA, not applicable.
a Administered 30 min before LVSΔguaB vaccination.
b Administered 28 d before F. tularensis infection.