Table 2.
Purity of Samples and Frequency of Human Immunodeficiency Virus (HIV) Genomes Detected
| Donor | 104 Cells Analyzed (95% CI) | Percentage of CD133+ Cells (95% CI) | Percentage of CD3+ T Cells (95% CI) | HIV Genomes Detected, No. | Frequency of HIV Genomes per 105 Cells In Vivo (95% CI) |
|---|---|---|---|---|---|
| CD133-sorted samples | |||||
| 303000 | 14 (9.7–17) | 98.8 (98.4–99.0) | .05 (.01–.14) | 0 | <.71 (0–3.8) |
| 304000 | 2.7 (2.4–3.0) | 84.4 (81.6–86.9) | .80 (.29–1.7) | 1 | 3.7 (.084–23) |
| 305000 | 6.0 (5.6–6.4) | 94.1 (93.3–94.9) | .59 (.36–.89) | 1 | 1.7 (.040–9.9) |
| 306000 | 5.4 (4.8–6.0) | 94.3 (93.5–95.0) | .62 (.39–.94) | 0 | <1.9 (0–7.7) |
| 307000 | 12 (11–13) | 93.2 (92.5–93.8) | .22 (.12–.38) | 0 | <.83 (0–3.3) |
| 308103 | 1.4 (1.0–1.7) | 92.1 (90.2–93.8) | .23 (.03–.82) | 0 | <7.1 (0–37) |
| 311000 | 4.1 (3.6–4.5) | 97.7 (97.1–98.3) | .83 (.51–1.3) | 1 | 2.5 (.057–15) |
| 312101 | 8.4 (5.9–11) | 98.9 (98.7–99.1) | .06 (.02–.15) | 1 | 1.2 (.023–9.5) |
| 313212 | 5.4 (4.3–6.5) | 98.4 (98.0–98.7) | .29 (.16–.48) | 1 | 1.9 (.039–13) |
| 314000 | .96 (.83–1.1) | 85.8 (81.4–89.5) | .65 (.08–2.3) | 0 | <10.4 (0–44) |
| 315214 | .48 (.35–.61) | 92.4 (89.4–94.8) | .76 (.16–2.2) | 3 | 63 (10–250) |
| CD133-depleted samples | |||||
| 303000 | 18 (13–23) | 5.0 (4.0–6.2) | 36 (34–38) | 2 | 1.1 (.11–5.7) |
| 304000 | 4.0 (3.6–4.3) | .18 (.01–1.5) | 61 (56–66) | 0 | <2.5 (0–10) |
| 305000 | 17 (14–20) | .13 (.03–.43) | 52 (50–54) | 0 | <.59 (0–2.7) |
| 306000 | 1.8 (1.7–2.0) | .31 (.08–1.1) | 73 (70–76) | 0 | <5.6 (0–22) |
| 307000 | 13 (12–14) | 1.6 (1.0–2.4) | 43 (40–46) | 1 | .77 (.017–4.8) |
| 308103 | 1.1 (.90–1.2) | <.19 (0–.69) | 75 (71–79) | 2 | 19 (2.0–80) |
| 311000 | 2.5 (2.1–2.9) | <.20 (0–.74) | 58 (54–63) | 2 | 8.1 (.84–35) |
| 312101 | 5.4 (4.7–6.0) | <.30 (0–1.1) | 44 (38–49) | 0 | <1.9 (0–7.8) |
| 313212 | 3.1 (2.4–3.8) | <.15 (0–.55) | 59 (55–63) | 0 | <3.2 (0–15) |
| 314000 | .54 (.42–.66) | <.21 (0–.76) | 82 (78–85) | 1 | 19 (.38–130) |
| 315214 | .41 (.32–.50) | <.22 (0–.79) | 81 (77–84) | 2 | 49 (4.9–224) |
Abbreviation: CI, confidence interval.