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. Author manuscript; available in PMC: 2013 May 15.
Published in final edited form as: Alcohol. 2010 Jan 6;44(0):673–690. doi: 10.1016/j.alcohol.2009.10.002

Table 2.

Differentially regulated placental genes, filtered by statistical significance and fold change of more than five

Affymetrix ID Symbol RefSeq Downregulated gene name Fold Δ
1369113_at GREM1 NM_019282 Gremlin 1, cysteine knot superfamily homolog –25.3
1385568_at DIO2 NM_031720 Deiodinase, iodothyronine type 2 –25.2
1387088_at GAL NM_033237 Galanin –21.4
1368731_at ORM1 NM_053288 Orosomucoid 1 –17.0
1388269_at HBG1 NM_172093 Hemoglobin, gamma A –16.2
1390112_at EFEMP1 NM_001012039 EGF-containing fibulin-like extracellular matrix protein 1 –15.8
1369677_at CNR1 NM_012784 Cannabinoid receptor 1 –15.5
1368304_at FMO3 NM_053433 Flavin-containing monooxygenase 3 –14.2
1368394_at SFRP4 NM_053544 Secreted frizzled-related protein 4 –13.9
1368912_at TRH NM_013046 Thyrotropin-releasing hormone –13.3
1398688_at SPINK5 XM_341607 Serine peptidase inhibitor, Kazal type 5 –10.7
1374558_at ICOSLG XM_574731 Inducible T-cell co-stimulator ligand –9.31
1387563_at PGR NM_022847 Progesterone receptor –9.21
1369625_at AQP1 NM_012778 Aquaporin 1 –9.15
1367846_at S100A4 NM_012618 S100 calcium binding protein A4 –8.78
1367627_at GATM NM_031031 Glycine amidinotransferase –8.26
1370843_at GNG8 NM_139185 Guanine nucleotide binding protein (G-protein), gamma 8 –8.25
1369695_at WT1 NM_031534 Wilms tumor 1 –8.14
1393069_at SFRP5 XM_219887 Secreted frizzled-related protein 5 –7.86
1369164_a_at TRPC4 NM_080396 Transient receptor potential cation channel 4C –7.63
1387450_at TGFA NM_012671 Transforming growth factor, alpha –7.62
1371102_x_at HBD NM_033234 Hemoglobin, delta –7.35
1369817_at HAND2 NM_022696 Heart and neural crest derivatives expressed 2 –6.97
1388270_at HBE1 NM_001008890 Hemoglobin, epsilon 1 –6.91
1368919_at PGF NM_053595 Placental growth factor –6.46
1396407_at GAS8 NM_001039030 Growth arrest-specific 8 –6.43
1380206_at KIF5C XM_221307 Kinesin family member 5C –6.32
1367600_at DES NM_022531 Desmin –6.23
1370157_at PLN NM_022707 Phospholamban –6.03
1388138_at THBS4 XM_342172 Thrombospondin 4 –5.69
1367794_at A2M NM_012488 Alpha-2-macroglobulin –5.62
1387656_at SLC4A1 NM_012651 Solute carrier family 4, anion exchanger, member 1 –5.60
1368713_at MMP10 NM_133514 Matrix metalloproteinase 10 (Stromelysin 2) –5.49
1370956_at DCN NM_024129 Decorin –5.37
1380285_at CHRD NM_001024273 Chordin –5.36
1368342_at AMPD3 NM_031544 Adenosine monophosphate deaminase (isoform E) –5.18
Affymetrix ID Symbol RefSeq Upregulated gene name Fold Δ
1380134_at VTCN1 NM_001024244 V-set domain containing T-cell activation inhibitor 1 5.08
1370594_at IGSF1 NM_175763 Immunoglobulin superfamily, member 1 6.00
1370077_at INS NM_019130 Insulin 6.67
1370165_at SMPX NM_053395 Small muscle protein, X-linked 13.7