Table 3.
Thirty-one differentially regulated genes in the “Nervous System Development Ontology Category”
| Affymetrix ID | Symbol | Fold Δ | Gene |
|---|---|---|---|
| 1387088_at | GAL | –21.4 | Galanin |
| 1370843_at | GNG8 | –8.25 | G-protein gamma 8 |
| 1380172_at | KIF5C | –6.36 | Kinesin 5C |
| 1388138_at | THBS4 | –5.70 | Thrombospondin 4 |
| 1380285_at | CHRD | –5.36 | Chordin |
| 1386903_at | S100B | –4.93 | S100 protein B |
| 1387659_at | GDA | –4.33 | Guanine deaminase |
| 1368914_at | RUNX1 | –3.93 | Runt-related transcription factor 1 |
| 1377336_at | SEMA3B | –3.31 | Sema domain, immunoglobulin domain (IG) |
| 1367668_a_at | SCD2 | –2.90 | Stearoyl-coenzyme A desaturase 2 |
| 1368721_at | ASCL2 | –2.67 | Achaete-scute complex homolog 2 |
| 1370236_at | PPT1 | –2.58 | Palmitoyl-protein thioesterase |
| 1376973_at | SDCBP2 | –2.44 | Syndecan binding protein 2 |
| 1369977_at | UCHL1 | –2.40 | Ubiquitin carboxy-terminal hydrolase 11 |
| 1369012_at | INHBA | –2.38 | Inhibin beta A |
| 1388427_at | MXRA8 | –2.24 | Limitrin |
| 1385013_at | WNT1 | –2.22 | Wingless-related MMTV integration site 1 |
| 1390233_at | Gli2 | –2.20 | GLI-Kruppel Family member GLI2 |
| 1390882_at | Heyl | –2.20 | Hairy/enhancer-of-split related with YRPW motif-like |
| 1387271_at | PHYH | –2.13 | Phytanoyl-CoA hydroxylase |
| 1369640_at | GJA1 | –2.11 | Gap junction protein, alpha 1 |
| 1382511_at | E2F1 | –2.07 | E2F transcription factor 1 |
| 1384667_x_at | GALR2 | –2.05 | Galanin receptor 2 |
| 1368254_a_at | SPHK1 | –2.04 | Sphingosine kinase 1 |
| 1372690_at | RTN4RL1 | –2.02 | Reticulon 4 receptor-like 1 |
| 1386943_at | PLLP | 2.03 | Transmembrane 4 superfamily, member 11 |
| 1375849_at | RGMA | 2.05 | Rgm domain family, member A |
| 1387232_at | BMP4 | 2.13 | Bone morphogenic protein 4 |
| 1383981_at | TRP53BP | 2.16 | Transformation-related binding protein 53 |
| 1389066_at | DSCR1L1 | 2.22 | Regulator of calcineurin 2 |
| 1382965_at | AMIGO3 | 2.68 | Amphoterin induced gene ORF 3 |
The enrichment factor for this category was 1.8, as determined by the ratio between the expected number of genes to the observed number of altered genes (P = .0016).