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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Nat Genet. 2013 Jan 13;45(2):180–185. doi: 10.1038/ng.2509

Figure 2.

Figure 2

Validation and recurrence of NAB2-STAT6 gene fusions in SFT. (a) RT-PCR and capillary sequencing of the index case and additional SFT cases using primers for NAB2 exon 6 and STAT6 exon 19. The sequencing trace of the index case (right) shows the chimeric junction between NAB2 and STAT6. (b) Genomic long-range PCR of the index case confirming the existence of the NAB2-STAT6 gene fusion at the DNA level. Gel electrophoresis of the amplified product (left, arrow) and schematic of exon-intron structure of the index NAB2-STAT6 gene fusion (right) are shown. (c) Schematics of additional NAB2-STAT6 gene fusions identified by transcriptome sequencing of 6 SFT samples.