. Author manuscript; available in PMC: 2014 Feb 23.

Published in final edited form as: J Pharm Biomed Anal. 2012 Oct 22;74:10.1016/j.jpba.2012.10.016. doi: 10.1016/j.jpba.2012.10.016

Table 4.

Recovery and ion-suppression

Metabolites	Nominal Concentrations (ng/mL)	Extraction recovery	Ion suppression recovery

		Mean ± S.D. (%)	Mean ± S.D. (%)
Acetaminophen	10	70.6 ± 2.2	100.1 ± 5.5
	40	72.3 ± 1.7	94.8 ± 2.5
	80	74.2 ± 3.4	97.2 ± 4.6
4′-Hydroxy diclofenac	100	57.4 ± 2.6	99.5 ± 6.6
	400	66.1 ± 7.2	97.8 ± 9.6
	800	65.1 ± 2.2	103.3 ± 10.2
4-Hydroxy mephenytoin	20	83.9 ± 8.1	96.4 ± 11.6
	60	90.3 ± 5.9	106.0 ± 8.0
	100	85.4 ± 9.8	102.6 ± 11.0
Dextrorphan	2	75.6 ± 3.4	102.9 ± 6.5
	10	82.9 ± 1.4	98.4 ± 6.9
	50	82.1 ± 2.7	102.1 ± 5.9
1′-Hydroxy midazolam	10	90.0 ± 6.2	72.5 ± 5.2
	40	93.3 ± 2.1	73.7 ± 2.4
	80	88.4 ± 2.9	74.9 ± 2.8